05 December 2017

Google expands its 3D objects pipeline for AR/VR with the Poly API


 Though Google’s early efforts in VR and AR may not have reached the average Android user, as the company scales its vision for what augmented and virtual reality mean to its overall business, it’s been devoting major attention as of late to the developers that have taken to building early experiences. Today, the company announced an extension to their ever-expanding pipeline for… Read More
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Vidme Shuts Down Because Google and Facebook


Vidme is shutting down, and it’s all the fault of Google and Facebook. The popular online video platform will go offline on December 15th, 2017, at which point all videos will be “permanently deleted from the Vidme servers”. And with that, Google and Facebook’s stranglehold tightens. A Brief History of Vidme Vidme was launched in 2014. It originally offered a simplified take on the idea of online video-sharing, with people able to upload videos anonymously without needing to register. It then evolved into a hybrid of YouTube and Reddit, with curated categories and content creators. The site attracted millions of...

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Google’s newest app stops you burning through your data package


 Google’s newest app for emerging markets is a service that helps control data usage on a smartphone and get more for your top-up credit. Datally, which is available for Android devices worldwide from today, applies granular control to enable a user to monitor use of data on their phone and cut data usage on any app as they please. The app design is simple and it appears to be effective.… Read More
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Target launches its own mobile payments system with debut of ‘Wallet’


 As promised earlier, Target today launched its own mobile payments system with the introduction of “Wallet” in the Target app. Wallet, as the name implies, allows Target shoppers in-store to both check out using their smartphone as well as take advantage of their Cartwheel digital coupons and discounts with only one scan of their barcode. Already, Cartwheel savings in… Read More

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DeepVariant: Highly Accurate Genomes With Deep Neural Networks




(Crossposted on the Google Open Source Blog)

Across many scientific disciplines, but in particular in the field of genomics, major breakthroughs have often resulted from new technologies. From Sanger sequencing, which made it possible to sequence the human genome, to the microarray technologies that enabled the first large-scale genome-wide experiments, new instruments and tools have allowed us to look ever more deeply into the genome and apply the results broadly to health, agriculture and ecology.

One of the most transformative new technologies in genomics was high-throughput sequencing (HTS), which first became commercially available in the early 2000s. HTS allowed scientists and clinicians to produce sequencing data quickly, cheaply, and at scale. However, the output of HTS instruments is not the genome sequence for the individual being analyzed — for humans this is 3 billion paired bases (guanine, cytosine, adenine and thymine) organized into 23 pairs of chromosomes. Instead, these instruments generate ~1 billion short sequences, known as reads. Each read represents just 100 of the 3 billion bases, and per-base error rates range from 0.1-10%. Processing the HTS output into a single, accurate and complete genome sequence is a major outstanding challenge. The importance of this problem, for biomedical applications in particular, has motivated efforts such as the Genome in a Bottle Consortium (GIAB), which produces high confidence human reference genomes that can be used for validation and benchmarking, as well as the precisionFDA community challenges, which are designed to foster innovation that will improve the quality and accuracy of HTS-based genomic tests.
For any given location in the genome, there are multiple reads among the ~1 billion that include a base at that position. Each read is aligned to a reference, and then each of the bases in the read is compared to the base of the reference at that location. When a read includes a base that differs from the reference, it may indicate a variant (a difference in the true sequence), or it may be an error.
Today, we announce the open source release of DeepVariant, a deep learning technology to reconstruct the true genome sequence from HTS sequencer data with significantly greater accuracy than previous classical methods. This work is the product of more than two years of research by the Google Brain team, in collaboration with Verily Life Sciences. DeepVariant transforms the task of variant calling, as this reconstruction problem is known in genomics, into an image classification problem well-suited to Google's existing technology and expertise.
Each of the four images above is a visualization of actual sequencer reads aligned to a reference genome. A key question is how to use the reads to determine whether there is a variant on both chromosomes, on just one chromosome, or on neither chromosome. There is more than one type of variant, with SNPs and insertions/deletions being the most common. A: a true SNP on one chromosome pair, B: a deletion on one chromosome, C: a deletion on both chromosomes, D: a false variant caused by errors. It's easy to see that these look quite distinct when visualized in this manner.
We started with GIAB reference genomes, for which there is high-quality ground truth (or the closest approximation currently possible). Using multiple replicates of these genomes, we produced tens of millions of training examples in the form of multi-channel tensors encoding the HTS instrument data, and then trained a TensorFlow-based image classification model to identify the true genome sequence from the experimental data produced by the instruments. Although the resulting deep learning model, DeepVariant, had no specialized knowledge about genomics or HTS, within a year it had won the the highest SNP accuracy award at the precisionFDA Truth Challenge, outperforming state-of-the-art methods. Since then, we've further reduced the error rate by more than 50%.
DeepVariant is being released as open source software to encourage collaboration and to accelerate the use of this technology to solve real world problems. To further this goal, we partnered with Google Cloud Platform (GCP) to deploy DeepVariant workflows on GCP, available today, in configurations optimized for low-cost and fast turnarounds using scalable GCP technologies like the Pipelines API. This paired set of releases provides a smooth ramp for users to explore and evaluate the capabilities of DeepVariant in their current compute environment while providing a scalable, cloud-based solution to satisfy the needs of even the largest genomics datasets.

DeepVariant is the first of what we hope will be many contributions that leverage Google's computing infrastructure and ML expertise to both better understand the genome and to provide deep learning-based genomics tools to the community. This is all part of a broader goal to apply Google technologies to healthcare and other scientific applications, and to make the results of these efforts broadly accessible.

Facebook Launches Messenger Kids for Children


Facebook has launched a new standalone version of Messenger aimed at kids. And it is, rather inevitably, called Messenger Kids. Messenger Kids is designed for children aged between six and 12, with parents being placed in charge of setting up and managing their children’s access. Thanks to the Children’s Online Privacy and Protection Act (COPPA) no one under the age of 13 is allowed to sign up for a Facebook account. Some kids still do sign up, but Facebook has needed a way to reach out to this younger generation without upsetting their parents for some time. A Child-Friendly Version...

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04 December 2017

You can now import your Instagram contacts into Messenger


 Facebook and Instagram have begun testing a feature that allows you to more easily bring your Instagram contacts into Messenger. The experience, which is entirely opt-in for the app’s users, is the latest in a series of integrations between Instagram and Facebook’s properties, which has earlier included the cross-posting of Instagram Stories to Facebook as well as the ability to… Read More
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9 Ridiculously Addictive Free Mobile Cartoon Games


Cartoons have made you laugh countless times on TV and online, but in game form? That’s right! You might not know it, but your favorite cartoons have been turned into some of the best and most entertaining mobile games on the market. Maybe it’s that classic cartoon style lends itself well to gaming, but these are seriously some of the most entertaining, most addicting, and most satisfying games to play on mobile. Read on to see the absolute best free games on the market fashioned after cartoons. 1. South Park: Phone Destroyer I can’t begin to measure how impressed I...

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Kinin puts aromatherapy in your mouth


 Kinin is a new portable aromatherapy vaporizer that, in theory, offers a refreshing break from THC and nicotine based vapes. Multi-use products let you inhale the strange fragrances of “Narrow leaf eucalyptus,” “Polynesian kava kava,” and “nootropics.” The product is part of the new trend toward healthier vaping and is aimed at yoga lovers and other… Read More

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How to Password Protect a PDF: Free and Paid Options


Did you know that you can password protect PDFs? This underused PDF feature is great for when you have to email and sign sensitive forms or contracts. We’ll show you free and professional tools to add a password to your PDF. Do you know of other methods and tools to secure PDFs? Please share in the comments below! How to Password Protect PDFs With Adobe Acrobat Pro DC Adobe Acrobat Pro DC is a full-service PDF creation suite. It’s $14.99 per month after a seven-day free trial. Besides making and editing PDFs, you can password protect PDFs in Adobe Acrobat...

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10 Tips for Building an Audience for Your Live Streaming Channel


live-stream

With YouTube ads not providing the revenue they once did, many gaming video creators are supplementing their output with live streaming as well. But it’s not quite the same as pre-recorded videos. When playing live, there are some different strategies you should take to retain an audience. But never fear, we have some advice for those looking to create or grow a live streaming channel. Here are 10 tips for growing (and retaining) your live stream audience: 1. Find Trending Games, But Not Oversaturated Ones When starting out with live streaming on Twitch or other platforms, you’ll want to choose new...

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The Sun Exchange funds solar installations with micro-investments and bitcoin


 Solar power could transform small communities around the world, but remote villages can’t always scrape together the thousands of dollars required to install the cells. The Sun Exchange wants to change that by leveraging the hearts and wallets of hobby investors, who cover the installation costs and then have their share of the revenue trickle in for years to come. There’s even… Read More

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Should You Use a Window Manager as Your Desktop Environment?


The general look of some operating systems remain the same, regardless of what you do to them. Linux is different in that regard, with a very high level of flexibility at its core. Each computer running it can vary wildly in both looks, and behavior. As such, it’s easy to have something on Linux that’s suited just for you. This can be hard to do though, if you’re not sure what you’re looking for. This applies even more if you’re using something a bit unique. In this case, using a window manager as your desktop environment. If you’re considering this...

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You Should Be Using the Nest App (Here’s Why)


Nest Labs is one of the biggest names in the smart home industry thanks to its iconic Nest Learning Thermostat. Since launching in 2010, the company has released various smart products, including webcams, smoke detectors, security systems, and more. There’s one app you can use to control all of these products: the free Nest app for iOS and Android. But what exactly does the Nest app do? And what features does it offer? Keep reading to find out. Which Devices Are Supported? The Nest app currently supports the following smart home products: Thermostats: Nest Learning Thermostat, Nest Thermostat E Cameras:...

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OnePlus celebrates ‘The Last Jedi’ with a limited edition Star Wars 5T


 Star Wars has had a strange smartphone history. The franchise was a no brainer for the Motorola Droid — Verizon actually had to license the name from Lucasfilm, so it follows that a few R2D2 handsets followed over the years. More recently, Sharp, of all companies, scored the rights in time for Rogue One. With The Last Jedi a mere weeks away, it’s OnePlus’s time to shine, with… Read More

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Supercharge Your LinkedIn Feed: Follow These 15 Amazing Influencers


We all know LinkedIn as a place to keep on top of your professional network and search for job openings. But there’s plenty more to the platform than just that. One of my favorite features on LinkedIn is being able to follow influencers and thought leaders who are not just sharing interesting links with their followers, but also publishing valuable, insightful content directly on LinkedIn itself. Intrigued? Follow a few of these popular influencers to keep your LinkedIn feed overflowing with fascinating, insightful content from some of the world’s most respected industry leaders. 1. Richard Branson Needing no introduction, Richard...

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Broadcom piles fresh pressure on Qualcomm to talk takeover


 Last month Qualcomm rejected a $70 per share acquisition offer from Broadcom — but the rival chipmaker isn’t stepping away. Today it’s announced it’s nominated a slate of eleven directors for Qualcomm’s board. Read More

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Facebook “Messenger Kids” lets under-13s chat with whom parents approve


 For the first time, Facebook is opening up to children under age 13 with a privacy-focused app designed to neutralize child predator threats that plague youth-focused competitors like Snapchat. Rolling out today on iOS in the US, “Messenger Kids” lets parents download the app on their child’s phone or tablet, create a profile for them, and approve friends and family who they… Read More
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ftcash helps Indian businesses accept cashless payments and loans them money


 A Mumbai-based startup called ftcash is helping small businesses in India move beyond cash. In some cases, it’s also providing loans to fund their operations. Co-founder Vaibhav Lodha, who demonstrated ftcash on-stage today at TechCrunch’s Startup Battlefield, said he first got the idea from his newspaper vendor, who complained that none of his customers seemed to have the cash at… Read More

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Facebook “Messenger Kids” lets under-13s chat with who parents approve


 For the first time, Facebook is opening up to children under age 13 with a privacy-focused app designed to neutralize child predator threats that plague youth-focused competitors like Snapchat. Rolling out today on iOS in the US, “Messenger Kids” lets parents download the app on their child’s phone or tablet, create a profile for them, and approve friends and family who they… Read More

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