Read Full Article
A blog about how-to, internet, social-networks, windows, linux, blogging, tips and tricks.
05 December 2017
Nvidia’s Shield TV offers Wii and GameCube games in HD in China
Read Full Article
Nintendo Switch vs. New 3DS XL: What Should You Buy?
If you’re thinking about buying a new portable game system, you’re probably deciding between the Nintendo Switch and the New Nintendo 3DS XL. While the PlayStation Vita has some solid games, Sony seems to have forgotten its portable system and thus it’s not too popular. We’re here to help you figure out whether the Switch or 3DS is better for you. Read on to learn about both systems so you know which one to get. An Introduction to Both Devices Let’s get some basic details out of the way before diving into the specifics of either system. The Switch is...
Read the full article: Nintendo Switch vs. New 3DS XL: What Should You Buy?
Read Full Article
Revolut merges mobile banking with cryptocurrency trading
Read Full Article
Heard This True Bill Gates Story About the History of Windows?
Here are 15 true stories and quotes about Bill Gates and the rise of Microsoft Windows. Bill Gates became internationally recognized over the 1980s and 1990s thanks to his part in making personal computers a hugely important component of modern life. His exploits have been collected in books, movies, and countless interviews. Here are some of the most illuminating looks at a major figure in the history of computing. Gates has clearly changed a lot over the last thirty years, and some of these stories show just how different today’s philanthropist is from yesterday’s ruthless businessman. 1. Bill Is Pretty...
Read the full article: Heard This True Bill Gates Story About the History of Windows?
Read Full Article
MGCool Explorer 2C Action Camera Review – Cheap as Chips, and Records in 4K
Our verdict of the MGCool Explorer 2C:If you want a cheap action camera that shoots excellent video without any bells and whistles, then this is the camera for you! Don't buy it if you're after slow motion or a wonderful user experience.710The MGCool Explorer 2C is a tiny, $80 action camera. It has a built in stabilizer, is waterproof, and can shoot Ultra-HD 4k video. It’s cheap, but do you get what you paid for? Features The Explorer 2C will be instantly familiar to anyone who has used a GoPro before. Its tiny size measures 60mm x 40mm x 30mm, or...
Read the full article: MGCool Explorer 2C Action Camera Review – Cheap as Chips, and Records in 4K
Read Full Article
Parents: Entertain Bored Kids Anywhere With These 12 Games
Maybe you and your child are on a long road trip, sitting in a waiting room, or traveling on public transportation. It doesn’t take long for an adult to become bored in these situations, much less a child. Technology brings us many benefits — these include ways to keep our kids entertained when they are stuck without toys, their favorite book, or their bike. If you allow your child to use your mobile device or they are lucky enough to have one of their own, then use it to your advantage. Instead of listening to “Are we there yet?” or...
Read the full article: Parents: Entertain Bored Kids Anywhere With These 12 Games
Read Full Article
Did You Know About These Gmail Limitations?
You live inside the Gmail inbox, but are you aware of its limitations and restrictions? For instance, did you know that Gmail has a sending limit? As soon as you hit the maximum number of emails, Gmail will put up a stop sign and won’t allow any more for the day. The reason behind this is online safety. The sending and receiving limits are designed to keep your account safe from spam attacks and excess automated messages. As soon as you hit the limit, you cannot receive any new email. All incoming messages are bounced back to the sender. Gmail’s Sending...
Read the full article: Did You Know About These Gmail Limitations?
Read Full Article
YouTube promises to increase content moderation staff to over 10K in 2018
Read Full Article
How to Cancel Your Xbox Live Subscription
Xbox Live Gold offers several benefits, like free games each month and online multiplayer. The $60 price tag for a year of service isn’t cheap though (especially if you can’t find a discount). Maybe you don’t bother with the free games or play online anymore. If you decide that you’re done with Xbox Live, it’s easy enough to cancel your subscription. How to Cancel Your Xbox Live Subscription Visit the Xbox website and click Sign in in the top-right corner. Sign into your Microsoft account. You’ll see your profile picture in the top-right corner of the page. Click it and...
Read the full article: How to Cancel Your Xbox Live Subscription
Read Full Article
How to Delete Old Windows Update Files
After what feels like an eternity, Microsoft has found a solution to the Windows updates conundrum — and more amazingly, users are happy with it. Windows Update now relies on a combination of active hours, customizable restarts, and manual pauses. The upshot is you can be safe in the knowledge that you’re running the latest version of the operating system without worrying about checking for updates every day. But there is still one part of Windows Update that needs your attention: the old files that are left behind. They can take up a lot of space. Rather than relying on Windows...
Read the full article: How to Delete Old Windows Update Files
Read Full Article
Google’s lightweight OS Android Go launches as Android Oreo (Go Edition)
Read Full Article
Google’s lightweight OS Android Go launches as Android Oreo (Go Edition)
Read Full Article
5 Household Hacks and DIY Experts Who Help Organize Your Home
It’s a hard job to keep your home clean and organized, but it’s a job that needs to be done. Still, with a few tricks and hacks, you can make this much easier than it is. Check out these household hacking experts for tips. While these bloggers are Americans, the tips aren’t for American households alone. Most of them are generic and applicable anywhere in the world, like saving money while decorating your home. 1. One Good Thing by Jillee Jill Nystul’s tips and tricks, found at her blog, have made her internet famous already. A simple writing style, plenty...
Read the full article: 5 Household Hacks and DIY Experts Who Help Organize Your Home
Read Full Article
Apple Pay Cash starts rolling out to iPhone users in the U.S.
Read Full Article
Google expands its 3D objects pipeline for AR/VR with the Poly API
Read Full Article
Vidme Shuts Down Because Google and Facebook
Vidme is shutting down, and it’s all the fault of Google and Facebook. The popular online video platform will go offline on December 15th, 2017, at which point all videos will be “permanently deleted from the Vidme servers”. And with that, Google and Facebook’s stranglehold tightens. A Brief History of Vidme Vidme was launched in 2014. It originally offered a simplified take on the idea of online video-sharing, with people able to upload videos anonymously without needing to register. It then evolved into a hybrid of YouTube and Reddit, with curated categories and content creators. The site attracted millions of...
Read the full article: Vidme Shuts Down Because Google and Facebook
Read Full Article
Google’s newest app stops you burning through your data package
Read Full Article
Target launches its own mobile payments system with debut of ‘Wallet’
Read Full Article
DeepVariant: Highly Accurate Genomes With Deep Neural Networks
Posted by Mark DePristo and Ryan Poplin, Google Brain Team
(Crossposted on the Google Open Source Blog)
Across many scientific disciplines, but in particular in the field of genomics, major breakthroughs have often resulted from new technologies. From Sanger sequencing, which made it possible to sequence the human genome, to the microarray technologies that enabled the first large-scale genome-wide experiments, new instruments and tools have allowed us to look ever more deeply into the genome and apply the results broadly to health, agriculture and ecology.
One of the most transformative new technologies in genomics was high-throughput sequencing (HTS), which first became commercially available in the early 2000s. HTS allowed scientists and clinicians to produce sequencing data quickly, cheaply, and at scale. However, the output of HTS instruments is not the genome sequence for the individual being analyzed — for humans this is 3 billion paired bases (guanine, cytosine, adenine and thymine) organized into 23 pairs of chromosomes. Instead, these instruments generate ~1 billion short sequences, known as reads. Each read represents just 100 of the 3 billion bases, and per-base error rates range from 0.1-10%. Processing the HTS output into a single, accurate and complete genome sequence is a major outstanding challenge. The importance of this problem, for biomedical applications in particular, has motivated efforts such as the Genome in a Bottle Consortium (GIAB), which produces high confidence human reference genomes that can be used for validation and benchmarking, as well as the precisionFDA community challenges, which are designed to foster innovation that will improve the quality and accuracy of HTS-based genomic tests.
open source release of DeepVariant, a deep learning technology to reconstruct the true genome sequence from HTS sequencer data with significantly greater accuracy than previous classical methods. This work is the product of more than two years of research by the Google Brain team, in collaboration with Verily Life Sciences. DeepVariant transforms the task of variant calling, as this reconstruction problem is known in genomics, into an image classification problem well-suited to Google's existing technology and expertise.
| Each of the four images above is a visualization of actual sequencer reads aligned to a reference genome. A key question is how to use the reads to determine whether there is a variant on both chromosomes, on just one chromosome, or on neither chromosome. There is more than one type of variant, with SNPs and insertions/deletions being the most common. A: a true SNP on one chromosome pair, B: a deletion on one chromosome, C: a deletion on both chromosomes, D: a false variant caused by errors. It's easy to see that these look quite distinct when visualized in this manner. |
DeepVariant is being released as open source software to encourage collaboration and to accelerate the use of this technology to solve real world problems. To further this goal, we partnered with Google Cloud Platform (GCP) to deploy DeepVariant workflows on GCP, available today, in configurations optimized for low-cost and fast turnarounds using scalable GCP technologies like the Pipelines API. This paired set of releases provides a smooth ramp for users to explore and evaluate the capabilities of DeepVariant in their current compute environment while providing a scalable, cloud-based solution to satisfy the needs of even the largest genomics datasets.
DeepVariant is the first of what we hope will be many contributions that leverage Google's computing infrastructure and ML expertise to both better understand the genome and to provide deep learning-based genomics tools to the community. This is all part of a broader goal to apply Google technologies to healthcare and other scientific applications, and to make the results of these efforts broadly accessible.
Facebook Launches Messenger Kids for Children
Facebook has launched a new standalone version of Messenger aimed at kids. And it is, rather inevitably, called Messenger Kids. Messenger Kids is designed for children aged between six and 12, with parents being placed in charge of setting up and managing their children’s access. Thanks to the Children’s Online Privacy and Protection Act (COPPA) no one under the age of 13 is allowed to sign up for a Facebook account. Some kids still do sign up, but Facebook has needed a way to reach out to this younger generation without upsetting their parents for some time. A Child-Friendly Version...
Read the full article: Facebook Launches Messenger Kids for Children
Read Full Article